Fluorescent in situ hybridization (FISH)

Studies on humans have shown that approximately 40-50% of early pregnancy loss results from unbalanced chromosome make-up in the conceptus. A majority of these losses occurs prior to implantation or within the first 4 weeks of pregnancy. The fluorescence in situ hybridization (FISH) technique using chromosome-specific DNA probes may be used to assess the numerical and structural chromosome aberrations in interphase cells.
 
In situ hybridization is a technique that allows the visualization of specific nucleic acid sequences within a cell. Specifically, DNA fluorescence in situ hybridization (FISH) involves the precise annealing of a single stranded fluorescently labeled DNA probe to complementary target sequences. The hybridization of the probe with the cellular DNA site is visibile by direct detection using fluorescence microscopy.

Do you want to know more?

Fill in this simple form and you will be contacted immediately

Name

Telephone

Messages


Accept the use of my personal data [Privacy Policy]


Folluow us